Journals > > Topics > RESEARCH PAPER
RESEARCH PAPER|7 Article(s)
Xue XIE, Jianrong WU, Xiaojun CAI, Junnian HAO, and Yuanyi ZHENG
Nanoparticles-based drug delivery system for synergetic chemo-photothermal therapy is an efficient strategy for tumor therapy. However, construction of nanodrugs with high drug loading capacity and good photothermal conversion property is still a great challenge. In this work, two-dimensional boron nanosheets were prepared by ultrasonic liquid exfoliation method, which were further loaded with ultra-small copper sulfide (CuS) nanoparticles and doxorubicin (DOX) to obtain B-CuS-DOX nanocomposites. The prepared B-CuS-DOX exhibited high drug loading capacity (864 mg/g) and excellent photothermal conversion efficiency (55.8%). In addition, B-CuS-DOX exhibited pH and laser--responsive drug release behavior. In vitro results demonstrated that the prepared B-CuS-DOX achieved a good synergistic effect of chemotherapy and photothermal therapy. This work is expected to provide an effective chemo-photothermal synergistic therapy strategy for tumor therapy. Nanoparticles-based drug delivery system for synergetic chemo-photothermal therapy is an efficient strategy for tumor therapy. However, construction of nanodrugs with high drug loading capacity and good photothermal conversion property is still a great challenge. In this work, two-dimensional boron nanosheets were prepared by ultrasonic liquid exfoliation method, which were further loaded with ultra-small copper sulfide (CuS) nanoparticles and doxorubicin (DOX) to obtain B-CuS-DOX nanocomposites. The prepared B-CuS-DOX exhibited high drug loading capacity (864 mg/g) and excellent photothermal conversion efficiency (55.8%). In addition, B-CuS-DOX exhibited pH and laser--responsive drug release behavior. In vitro results demonstrated that the prepared B-CuS-DOX achieved a good synergistic effect of chemotherapy and photothermal therapy. This work is expected to provide an effective chemo-photothermal synergistic therapy strategy for tumor therapy.
Journal of Inorganic Materials
- Publication Date: Jan. 20, 2021
- Vol. 36, Issue 1, 81 (2021)
Xiao YANG, Xianli SU, Yonggao YAN, and Xinfeng TANG
In general, (GeTe)n(Bi2Te3)m compounds in GeTe-Bi2Te3 pseudo-binary system possess a relatively low thermal conductivity, however, the thermoelectric properties of these compounds have not been evaluated systematically. In this study, a series of single-phase (GeTe)nBi2Te3 (n=10, 11, 12, 13, 14) compounds were prepared by a melting-quenching-annealing process combined with spark plasma sintering. The phase compositions and thermoelectrical properties of these samples were characterized. It is found that doping with Bi2Te3 intensifies the phonon scattering and significantly reduces the lattice thermal conductivities of these samples, producing a low total thermal conductivity of 1.63 W?m -1?K -1 at 723 K for (GeTe)13Bi2Te3 compound. Moreover, the effective mass of these compounds is enhanced through adjustment of the relative amount of Bi2Te3 and GeTe. Therefore, the Seebeck coefficient and power factor of these samples remain superior even at high carrier concentration. At 723 K, the maximum power factor of (GeTe)13Bi2Te3 compound is 2.88×10 -3 W?m -1?K -2 and the maximum ZT of (GeTe)13Bi2Te3 is 1.27, which is 16% higher than that of pristine GeTe. In general, (GeTe)n(Bi2Te3)m compounds in GeTe-Bi2Te3 pseudo-binary system possess a relatively low thermal conductivity, however, the thermoelectric properties of these compounds have not been evaluated systematically. In this study, a series of single-phase (GeTe)nBi2Te3 (n=10, 11, 12, 13, 14) compounds were prepared by a melting-quenching-annealing process combined with spark plasma sintering. The phase compositions and thermoelectrical properties of these samples were characterized. It is found that doping with Bi2Te3 intensifies the phonon scattering and significantly reduces the lattice thermal conductivities of these samples, producing a low total thermal conductivity of 1.63 W?m -1?K -1 at 723 K for (GeTe)13Bi2Te3 compound. Moreover, the effective mass of these compounds is enhanced through adjustment of the relative amount of Bi2Te3 and GeTe. Therefore, the Seebeck coefficient and power factor of these samples remain superior even at high carrier concentration. At 723 K, the maximum power factor of (GeTe)13Bi2Te3 compound is 2.88×10 -3 W?m -1?K -2 and the maximum ZT of (GeTe)13Bi2Te3 is 1.27, which is 16% higher than that of pristine GeTe.
Journal of Inorganic Materials
- Publication Date: Jul. 13, 2021
- Vol. 36, Issue 1, 75 (2021)
Yumin XIAO, Bin Li, Lizhao QIN, Hua LIN, Qing LI, and Bin LIAO
Copper germanate has attracted wide attention because of its spin-Peierls transition and excellent lithium storage performance. Typical hydrothermal method uses weak acid salts such as Cu(CH3COO)2 to promote the ionization of water to obtain OH - required for the growth of CuGeO3. Although the operation is facile, the reaction time is long and the efficiency is low. In this work, CuCl2 was used as the copper source instead of Cu(CH3COO)2 and the pH of precursor solution was adjusted to control the adsorption capacity of each crystal plane and the supersaturation of the solution, so as to achieve efficient preparation of CuGeO3 nanorods and CuGeO3 hexagonal nanosheets, effectively shortening the reaction time to 8 h. Based on this, one-dimensional structure-directing agent ethylenediamine was added to accelerate the reaction process while limiting the two-dimensional planar growth of CuGeO3, and six different sizes ( 100 nm, 200-300 nm, 350-500 nm, 400-700 nm, 1-2 μm and 1-3 μm) of uniform CuGeO3 nanowires were efficiently prepared. Copper germanate has attracted wide attention because of its spin-Peierls transition and excellent lithium storage performance. Typical hydrothermal method uses weak acid salts such as Cu(CH3COO)2 to promote the ionization of water to obtain OH - required for the growth of CuGeO3. Although the operation is facile, the reaction time is long and the efficiency is low. In this work, CuCl2 was used as the copper source instead of Cu(CH3COO)2 and the pH of precursor solution was adjusted to control the adsorption capacity of each crystal plane and the supersaturation of the solution, so as to achieve efficient preparation of CuGeO3 nanorods and CuGeO3 hexagonal nanosheets, effectively shortening the reaction time to 8 h. Based on this, one-dimensional structure-directing agent ethylenediamine was added to accelerate the reaction process while limiting the two-dimensional planar growth of CuGeO3, and six different sizes ( 100 nm, 200-300 nm, 350-500 nm, 400-700 nm, 1-2 μm and 1-3 μm) of uniform CuGeO3 nanowires were efficiently prepared.
Journal of Inorganic Materials
- Publication Date: Jun. 09, 2021
- Vol. 36, Issue 1, 69 (2021)
Yanran MENG, Xinger WANG, Jian YANG, Han XU, and Feng YUE
Architectural laminated glass exhibits significant vulnerability under hard body impacts such as windborne debris impacts. In this work, a prediction model is proposed for assessing the impact status of laminated glass under hard body impact. Multiple design variables including the glass make-ups, interlayer types, support conditions and size are considered. The impact tests with consecutive impact attempts are first conducted. A comprehensive database encompassing the failure condition of each glass layer is then established. This database has 567 groups of PVB laminated glass data and 210 groups of SGP laminated glass data. A combined WOA-KELM machining learning based model is subsequently developed to predict the impact status of laminated glass. The modelling results are compared with that from SVM and LSSVM based models. The results show that the proposed model has a prediction accuracy of 88.45% in failure status of each glass layer. Such model can well predict the impact status of laminated glass and shows better performance in both accuracy and computation cost than other models. Architectural laminated glass exhibits significant vulnerability under hard body impacts such as windborne debris impacts. In this work, a prediction model is proposed for assessing the impact status of laminated glass under hard body impact. Multiple design variables including the glass make-ups, interlayer types, support conditions and size are considered. The impact tests with consecutive impact attempts are first conducted. A comprehensive database encompassing the failure condition of each glass layer is then established. This database has 567 groups of PVB laminated glass data and 210 groups of SGP laminated glass data. A combined WOA-KELM machining learning based model is subsequently developed to predict the impact status of laminated glass. The modelling results are compared with that from SVM and LSSVM based models. The results show that the proposed model has a prediction accuracy of 88.45% in failure status of each glass layer. Such model can well predict the impact status of laminated glass and shows better performance in both accuracy and computation cost than other models.
Journal of Inorganic Materials
- Publication Date: Jun. 15, 2021
- Vol. 36, Issue 1, 61 (2021)
Denghao MA, Zhenhua HOU, Junping LI, Xin SUN, Enze JIN, and Jian YIN
Microstructure and static mechanical properties of 3D-SiC/SiC composites with different interfaces, such as PyC, SiC and PyC/SiC and without an interface were prepared via polymer infiltration and pyrolysis, and effect of interface type on the internal friction was investigted by means of forced vibration. The results showed that the microstructure and static mechanical properties of SiC/SiC composites with an interphase layer were superior to the composites without an interlayer, and the former also showed a lower internal friction than the later. The sub-layer SiC of the PyC/SiC interface limits the binding state and the plastic deformation of PyC interphase, beneficial to improving the mechanical properties of SiC/SiC composite. Meanwhile, The interface layer of SiC/SiC composites has a significant effect on the internal friction behavior, with interfacial shear strength inversely proportional to the internal friction. By comparing the change rate of internal friction of composites at 50 and 350 ℃, the overall trend of internal friction decreases with the increase of interfacial shear strength. In addition, as compared with the composite with PyC interface, the composite with PyC/SiC interface has a lower change rate of the internal fiction, indicating that PyC/SiC interface of SiC/SiC composites is more helpful for high temperature vibration environment. Microstructure and static mechanical properties of 3D-SiC/SiC composites with different interfaces, such as PyC, SiC and PyC/SiC and without an interface were prepared via polymer infiltration and pyrolysis, and effect of interface type on the internal friction was investigted by means of forced vibration. The results showed that the microstructure and static mechanical properties of SiC/SiC composites with an interphase layer were superior to the composites without an interlayer, and the former also showed a lower internal friction than the later. The sub-layer SiC of the PyC/SiC interface limits the binding state and the plastic deformation of PyC interphase, beneficial to improving the mechanical properties of SiC/SiC composite. Meanwhile, The interface layer of SiC/SiC composites has a significant effect on the internal friction behavior, with interfacial shear strength inversely proportional to the internal friction. By comparing the change rate of internal friction of composites at 50 and 350 ℃, the overall trend of internal friction decreases with the increase of interfacial shear strength. In addition, as compared with the composite with PyC interface, the composite with PyC/SiC interface has a lower change rate of the internal fiction, indicating that PyC/SiC interface of SiC/SiC composites is more helpful for high temperature vibration environment.
Journal of Inorganic Materials
- Publication Date: Jul. 21, 2021
- Vol. 36, Issue 1, 55 (2021)
Peng WAN, Mian LI, and Qing HUANG
Silicon carbide is widely used because of its excellent physical and chemical properties. The chemical bonding characteristics of SiC make it difficult to be sintered. Therefore, preparation of high-quality SiC ceramics is one of the challenges in SiC research field. In this study, the ternary rare-earth carbide Dy3Si2C2 was proposed as a new sintering additive for SiC ceramics, through the phase transition of Dy-Si-C system at high temperatures to promote the densification of SiC. The Dy3Si2C2 coated SiC powders were synthesized via an in-situ reaction between metal Dy and SiC in high temperature molten salts. The Dy3Si2C2 coated SiC powder was sintered by spark plasma sintering (SPS), at 1800 ℃, 45 MPa. As the result, high-purity SiC ceramic with the density of 99% and thermal conductivity of 162.8 W·m -1·K -1was obtained to form the SiC-Dy3Si2C2 raw material with n(Dy) : n(SiC)=1 : 4. Further study shows that Dy3Si2C2 and SiC undergo a eutectic reaction at high temperatures, which generates liquid phase at the grain boundaries and promotes the densification of SiC ceramics. This study shows that the ternary rare-earth carbides Re3Si2C2 (Re=La, Ce…) has great potential to be used as the sintering additive for SiC. Silicon carbide is widely used because of its excellent physical and chemical properties. The chemical bonding characteristics of SiC make it difficult to be sintered. Therefore, preparation of high-quality SiC ceramics is one of the challenges in SiC research field. In this study, the ternary rare-earth carbide Dy3Si2C2 was proposed as a new sintering additive for SiC ceramics, through the phase transition of Dy-Si-C system at high temperatures to promote the densification of SiC. The Dy3Si2C2 coated SiC powders were synthesized via an in-situ reaction between metal Dy and SiC in high temperature molten salts. The Dy3Si2C2 coated SiC powder was sintered by spark plasma sintering (SPS), at 1800 ℃, 45 MPa. As the result, high-purity SiC ceramic with the density of 99% and thermal conductivity of 162.8 W·m -1·K -1was obtained to form the SiC-Dy3Si2C2 raw material with n(Dy) : n(SiC)=1 : 4. Further study shows that Dy3Si2C2 and SiC undergo a eutectic reaction at high temperatures, which generates liquid phase at the grain boundaries and promotes the densification of SiC ceramics. This study shows that the ternary rare-earth carbides Re3Si2C2 (Re=La, Ce…) has great potential to be used as the sintering additive for SiC.
Journal of Inorganic Materials
- Publication Date: Jan. 20, 2021
- Vol. 36, Issue 1, 49 (2021)
Jiawei BAI, Jing YANG, Zhenfei LÜ, and Xiaodong TANG
Hexaferrite system is expected to be applied in various kinds of multi-state memories, magnetoelectric sensors and other new microelectronic devices, due to its high temperature magnetoelectric coupling effect with low field. Not only the B-site doping of M-type hexaferrite BaFe12O19 with Ti 4+ ion can change its magnetic structure and magnetic properties, but also the defects, multivalent Fe ions, introduced by B-site non-epuivalent Ti doping, could affect its electric properties. In this study, M-type hexaferrite BaFe12-xTixO19 (x=0, 0.5, 1, 1.5) ceramics were prepared by solid phase sintering. The effects of Ti 4+ doping on the structural, magnetic and dielectric properties were studied. The results show that BaFe12-xTixO19 is in ferrimagnetic order with antiparallel spins. When the doping concentration of Ti 4+ ions is low, it tends to replace Fe 3+ ions with up-spin. And the magnetization decreases with the increase of Ti dopant. However, with the further increase of Ti 4+ doping, Fe 3+ ions with down-spin is also replaced, and the saturation magnetization increases with the increase of x. The introduction of Ti 4+ ions can also make the grains to be semiconductor, which results in the Maxwell-Wagner interface polarization behavior at the interfaces between semiconducting grains and grain-boundaries. Hence, M-type hexaferrite BaFe12-xTixO19 ceramics appear obvious low frequency dielectric enhancement accompanied by a Maxwell-Wagner dielectric relaxation. Hexaferrite system is expected to be applied in various kinds of multi-state memories, magnetoelectric sensors and other new microelectronic devices, due to its high temperature magnetoelectric coupling effect with low field. Not only the B-site doping of M-type hexaferrite BaFe12O19 with Ti 4+ ion can change its magnetic structure and magnetic properties, but also the defects, multivalent Fe ions, introduced by B-site non-epuivalent Ti doping, could affect its electric properties. In this study, M-type hexaferrite BaFe12-xTixO19 (x=0, 0.5, 1, 1.5) ceramics were prepared by solid phase sintering. The effects of Ti 4+ doping on the structural, magnetic and dielectric properties were studied. The results show that BaFe12-xTixO19 is in ferrimagnetic order with antiparallel spins. When the doping concentration of Ti 4+ ions is low, it tends to replace Fe 3+ ions with up-spin. And the magnetization decreases with the increase of Ti dopant. However, with the further increase of Ti 4+ doping, Fe 3+ ions with down-spin is also replaced, and the saturation magnetization increases with the increase of x. The introduction of Ti 4+ ions can also make the grains to be semiconductor, which results in the Maxwell-Wagner interface polarization behavior at the interfaces between semiconducting grains and grain-boundaries. Hence, M-type hexaferrite BaFe12-xTixO19 ceramics appear obvious low frequency dielectric enhancement accompanied by a Maxwell-Wagner dielectric relaxation.
Journal of Inorganic Materials
- Publication Date: Jul. 21, 2021
- Vol. 36, Issue 1, 43 (2021)
Topics
© Copyright 2018-2021 | Chinese Laser Press. All Rights Reserved 沪ICP备15018463号-20